NAD+ (Nicotinamide Adenine Dinucleotide) – Premium Research Compound
NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in all living cells, serving as an essential cofactor in numerous metabolic reactions. This dinucleotide has become a focal point in metabolism, redox biology, and cellular energy research due to its central role in redox reactions and its function as a substrate for NAD-consuming enzymes.
This product is intended for laboratory and research purposes only. Research Use Only.
Molecular Characteristics
NAD+ consists of two nucleotides joined through their phosphate groups—one containing an adenine base and the other containing nicotinamide. The molecule exists in oxidized (NAD+) and reduced (NADH) forms, cycling between these states during metabolic processes. Endogenous NAD+ concentrations have been shown to vary across biological samples, making it a significant focus of metabolic and enzymatic research.
Research Applications
NAD+ has been extensively studied in various research contexts including:
- Cellular energy metabolism and mitochondrial function
- Sirtuin enzyme activation and regulation (SIRT1-7)
- DNA repair mechanisms through PARP enzyme activity
- Circadian rhythm regulation and metabolic homeostasis
- NAD+ flux dynamics across experimental models
- Neuronal signaling and NAD+-dependent pathway studies
- Metabolic pathway analysis and enzymatic studies
Research indicates NAD+ serves as a substrate for several important enzyme families including sirtuins, PARPs, and CD38, linking it to diverse cellular processes from gene expression to enzymatic regulation.
Technical Specifications
- CAS Number: 53-84-9
- Molecular Formula:C21H27N7O14P2
- Molecular Weight: 663.43 g/mol
- Purity: ?99%
- Form: Lyophilized powder
- Appearance: White to off-white powder
- Storage: Store at -20°C, protected from light and moisture



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